The Glamour Boys won the first leg of their preliminary round tie 1-0 against Cameroonian champions PWD Bamenda in Limbe on Sunday.
'Domza' says Amakhosi needed the win as everybody is against them these days following a poor start to the 2020/21 season on the domestic front.
"I'm happy for the results my brother, I always know that dark days won't last forever," Isaacs tells KickOff.com.
"To be honest brother Chiefs results, it affects a lot of people. If you love them, if you hate them, it affects a lot of people and it makes a lot of news. So I'm happy that they have won and put a smile to a lot of Kaizer Chiefs supporters and the followers.
"So ja I hope they have turned the corner now because it's positive. Maybe they needed something like this to turn a corner. Because even here in South Africa you check in the social media they are hammering Chiefs, everybody is just talking negatively about Chiefs. So they needed something like this. Maybe this is where they will turn the corner.
"In my opinion maybe they needed a change of scenery. Maybe it's a turning point for the season because yes they can't sign players but it's the same team that were runners-up until the last day last season.
"So for me they are a team that can challenge you know, the players themselves, it's only them who can take them out of the situation, nobody else. Kaizer Chiefs have got players that will always create chances. And a positive sign for me is that they kept a clean sheet, and that is the main thing."
The former centre-back believes Amakhosi are capable of reaching the Champions League group stages.
"Look, it's going to be very, very demanding you know. In competitions like this they also need luck of the draw," he adds.
"We see the importance of CAF ranking and FIFA ranking now. You know I'm an optimistic person and I don't see any reason why they cannot go to the group stages."