According to the former Santos player, it will be key for The Brazilians to back themselves throughout the 90 minutes.
"I don't think we should be too focused on our opponents," Arendse told snl24.com/kickoff from Egypt.
"We should play to our strengths because we have the firepower to beat Zamalek and we should back ourselves. We have skillful and players with pace that can make life difficult for them.
"To dictate the tempo of play will be key as well. It’s pointless if we're gonna try to out muscle them."
Arendse, who has filled the spot of Sundowns' former captain Alje Shut in the heart of the Brazilians defense with great aplomb since getting the nod from coach Pitso Mosimane, reckons they are well aware of the hostile reception from the North African team's home crowd.
"But we should be smart and outfox them and not be intimidated at all. As difficult as it will be we should try and block out what happens outside the playing field.
"I'm confident we can achieve a positive result against them," Arendse concludes.