All three goals were scored in the first half as Aboubacar Camara put Guinea in front, before Karl Ekambi equalised for the Indomitable Lions just past the half-hour mark.
Francois Kamano restored Guinea’s lead in first half injury-time, and they were able to hold on for a morale-boosting win.
Egypt kept up their excellent recent form with a 3-0 victory over Togo as Kahraba, Ahmed El Sheikh and Arsenal star Mohamed Elneny netted for The Pharaohs.
In an all-North African clash, Morocco edged Tunisia 1-0 thanks to an own goal from Hamza Younes.
