Dybala has featured in four Serie A matches this season but is yet to open his account for the campaign.
The 22-year-old was given a chance to start against Frosinone on Sunday and did not take the chance as goals from Cristiano Ronaldo and Federico Federico Bernardeschi secured the win.
“He needs to play. I’ve said since he arrived that his best physical quality is his running, so he needs to play and to move," Allegri was quoted as saying by FootballItalia.
"He had some good moves today, controlling on the edge of the box where there was traffic, but he needs to run at defenders and he’ll do that once his fitness levels improve.
“Dybala has no need to feel this performance anxiety. You can be the best player in the world, but if you’re not at 100 per cent mentally, the others will get to the ball faster. Mario Mandzukic is always first to the ball, but today he was a little less sharp because of fatigue, it’s natural.”