Buthelezi says Agents are the main reason the club is full of top earners who have never contributed even a single piece of silverware since their arrival.
"If Arthur Zwane needs success he must release all those who no longer have the heart to play for Kaizer Chiefs," Buthelezi tells KickOff.
"The issue of the Agents somehow needs to be scrutinised because making money with players who lack quality kills our team.
"The Agents will cripple Chiefs as they did with Bafana Bafana, they've done it with the national team in 1996 and at some stage, it crippled because other players were compromised.
"So at Chiefs Stuart Baxter brought his players and young boys like Nkosingiphile Ngcobo were compromised.
"I'd be glad if Bernard Parker, Khama Billiat and Keagan Dolly leave the club. Dolly was not supposed to be signed from the beginning he must go, he is fat like me."