The PSL is searching for a new sponsor following Absa South Africa's decision to terminate their 16-year relationship with South African football.
Matthews admits that just like football fans, the news left the clubs just as worried.
"Of course we are all worried about the current economic climate in the country and around the world," the SuperSport United CEO tells snl24.com/kickoff.
"The PSL can't be shielded from these harsh economic realities. As clubs we are going to have to make some serious adjustments around how to balance our books.
"So you can expect a lot of uncertainty in this space until a new league sponsor is announced and we can all bed down some stability at these uncertain times.
"I'm extremely sad to see the end of the Absa sponsorship. We won the old Absa Cup in 2005 and then the first three Absa Premierships (2008-2010) so you can forgive me for being biased.
"Absa have been incredible stakeholders in the PSL and are held in the highest regard by everyone. Their contribution has been immense and we need to reflect on it with gratitude and appreciation.
"It's unfortunate that their league sponsorship has ended but I'm confident that like all the PSL’s special longstanding relationships, Absa and the PSL will continue to find ways to collaborate to add value, excitement and legacy to the South African football landscape."
Asked if this might affect the grants received by clubs, Matthews said: "We have not been advised of any changes to our grant structure."