Meyiwa has only conceded two goals in five League matches since Josephs was sidelined with a minor shoulder injury and De Sa suggests Josephs has a big fight on his hands to reclaim a starting place.
"Moeneeb has been injured and hopefully he will start training on Monday to do a lot more goalkeeping work ... he has only been running," the coach says.
"For now, Senzo is the number one. He's doing well, he is playing well and he will hold on to his position. Until Moeneeb shows me he is ready to play a couple of reserve games and he is in top form, and Senzo loses his form, then we will change it.
"But Senzo is holding on to that spot and if he keeps performing, there will be no reason to change."
De Sa also explained why he opted for Andile Jali in midfield for the Soweto Derby instead of Thandani Ntshumayelo.
KickOff.com broke the news a few hours before kick-off on Saturday that Jali, who had not played a competitive match in four weeks since he got injured against Bloemfontein Celtic on November 4 in a Telkom Knockout clash, had got the nod ahead of Ntshumayelo, and the news was met with mixed feelings.
CJB Ramses III, who posted a comment to the story, said: "Ok..... Mixed feelings.... but it's ok.... A half fit Jali is still the best combative midfielder of this generation..."
De Sa explains: "It was touch and go between the two [Jali and Ntshumayelo], but I think because of the nature of the game it was important to play Andile because of his experience and I think he did pretty well.
"He hadn't played for the past four weeks, but he had been training so obviously we see what he's done at training. Ntshumayelo did pretty well in the last game [against Chippa United], but it was only 48 hours away from this game [the Derby] so it was difficult to play Ntshumayelo again in a game of this magnitude," De Sa adds.