The home side scored early in the first half with a goal from Peter Ndlovu.
Sundowns kept in front for most of the game until the 82nd minute when the Tunisians equalized through a header from Chadi Hammami.
Former Orlando Pirates midfielder Blaise Lelo-Mbele scored late in the match with a low shot to put his side into the final.
When Sundowns played Sfaxien in Tunisia in August they lost 4-0.
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