The goals were scored by Marawaan Bantam and Erwin Isaacs for Santos.
In the first half both sides were down to 10-men when they had David Radebe and Thembile Kanono sent off.
The match was fairly even territorially with Wits missing some good opportunities especially during the second half but overall a draw was probably a fair result.
Wits took the lead in the 3rd minute when Marawaan Bantam scored with a close-range header from a cross from the left by Rene Richards.
Both sides were down to 10-men midway through first half when they both had a man sent off for an off the ball incident. The players who were red-carded were David Radebe for Wits and Thembile Kanono for Santos.
In the 44th minute Santos equalized when a long-range shot along the ground by Erwin Isaacs somehow went under goalkeeper Moeneeb Josephs, who really should have saved the ball.
In the 56th minute Almiro Lobo nearly scored for Wits when his shot struck the bar.
The draw sees Santos near the bottom of the table on 4 points while Wits are near the top on 11 points.