AC Milan retained their two-point lead at the top of the Serie A table after beating Atalanta 2-0 in the penultimate match at Stadio Guiseppe Meazza.
After a goalless first stanza the hosts' persistence eventually paid off 11 minutes from the half-time break after Rafael Leao went on a solo run in the box and fired home a strike past goalkeeper Juan Musso.
Theo Hernandez secured the three points for Milan with the second goal in the last quarter of an hour after unleashing a low strike from the edge of the box that found the bottom corner.
Inter Milan kept their title hopes alive with a 3-1 victory over Cagliari at Unipol Domus.
Inter had an early goal scored by Milan Skriniar disallowed by the Video Assistant Referee (VAR) for a handball.
However, Matteo Darmian eventually broke the deadlock for the visitors in the 25th minute from a towering header in the box and Lautaro Martinez doubled their lead early in the second stanza with a powerful drive from the edge of the box.
Charalampos Lykogiannis pulled a goal back for Cagliari just two minutes later but Martinez made the result safe for Simeone Inzaghi's charges six minutes before time with a tap-in from a square pass by Roberto Gagliardini.
Napoli secured third position on the log and dented Genoa's chances of survival after a 3-0 drubbing at Stadio Diego Armando Maradona.
Victor Osimhen broke the deadlock for Napoli just after the half-hour mark with a header in the box after a cross by Giovanni Di Lorenzo.
Luciano Spalletti's charges were awarded a penalty for a handball in the box just after the hour-mark and although Lorenzo Insigne struck his spot-kick into the post, he got a second bite of the cherry from a retake and made no mistake.
Stanislav Lobotka sealed the three points for the Blues with the third goal nine minutes before time.
Sassuolo ended their four-game winless streak after thrashing Bologna 3-1 courtesy at Stadio Renato Dall'Ara.
Gianluca Scamacca broke the deadlock for Sassuolo ten minutes before the half-time break with a header from a corner.
Vlad Chiriches thought he had doubled their lead for the visitors on the hour-mark with a strike from a rebound but his goal was disallowed by Video Assistant Referee (VAR) for offside.
However, Domenico Berardi eventually made it 2-0 for Sassuolo in the last quarter of an hour with an over-head kick from a rebound in the box.
Scamacca sealed the deal for the visitors and grabbed his brace in the last ten minutes while Riccardo Orsolini scored a consolation goal for Bologna in stoppage time from the penalty spot awarded after a VAR review.